Exploring Hyperbaric Oxygen in Clinical Practice

A clinician-focused introduction to hyperbaric oxygen therapy, exploring pressure physiology, cellular mechanisms, safety, and practical applications for inflammation, neuroprotection, metabolic recovery, and complex patient care.

Human Performance & Regenerative Medicine

Matthew Antonucci

Level:

Explorer

Credit Hours:

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Description

This 1-credit exploratory course equips clinicians with a clear, practical understanding of how hyperbaric oxygen therapy (HBOT) influences the brain, immune system, and metabolic health. You’ll examine key gas laws, pressure dynamics, and oxygen physiology so you can appreciate HBOT’s unique ability to enhance mitochondrial output, stimulate angiogenesis, regulate inflammation, and protect vulnerable tissues. Through mechanisms such as sirtuin activation, redox modulation, and improved perfusion, HBOT becomes a strategic tool for supporting concussion, neurodegeneration, chronic infections, metabolic dysfunction, and tissue repair. You will also learn how to differentiate chamber types, select appropriate pressures, identify contraindications, and apply evidence-informed decision-making to real-world clinical scenarios. Designed for providers who treat complex neurological, inflammatory, and metabolic cases, this course expands your therapeutic strategies and strengthens your ability to integrate HBOT confidently and safely into modern clinical practice.

View syllabus

What you’ll learn:

Understand how pressure and oxygen physiology influence cellular repair and metabolic function.
Identify HBOT mechanisms supporting neuroprotection, inflammation control, and mitochondrial recovery.
Select appropriate pressures for neurological, infectious, and metabolic clinical presentations.
Recognize contraindications, risks, and safe implementation strategies for HBOT.
Compare chamber types to guide clinical adoption and patient communication.

Syllabus

Components

Topic 1 – Foundations of Hyperbaric Oxygen Therapy (HBOT)
- A clinician-centered overview of HBOT’s mechanisms, dispelling misconceptions and aligning understanding with real-world physiology and regulatory considerations.
Topic 2 – Gas Laws, Pressure Dynamics & Clinical Physics
- Break down Boyle’s and Henry’s laws as applied to therapeutic gases, enabling precise clinical reasoning behind dosing, pressure selection, and tissue outcomes.
Topic 3 – Cellular & Mitochondrial Mechanisms of HBOT
- Explore how HBOT enhances mitochondrial output, regulates redox potential, activates sirtuin pathways, and inhibits cell-death mechanisms tied to neurological and metabolic disorders.
Topic 4 – Anti-Inflammatory, Angiogenic & Neuroregenerative Effects
- Understand HBOT’s ability to modulate immune activity, reduce NF-kappa-beta, support neurogenesis, and stimulate vascular repair for complex clinical cases.
Topic 5 – Clinical Indications, Contraindications & Safety
- Practical guidance on selecting appropriate pressures, identifying absolute/relative contraindications, and mitigating side effects such as barotrauma or oxygen toxicity.
Topic 6 – Chamber Types, Pressures & Real-World Implementation
- Compare monoplace vs. multiplace chambers, mild vs. moderate vs. high pressure applications, and how to strategically prescribe HBOT based on immune, metabolic, or neurological goals

Live Event Info

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Online

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Also includes

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Months Medline Access

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Months of Access to Complete the course (from the date of purchase)

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Ability to resubscribe to keep access after

months

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Eligibility for Neurology Fellowship and Diplomate Examinations after the completion of 300+ hours of study

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Certificate of Completion