Courses

Beyond Hunger: Ghrelin, the Gut–Brain Axis, and a New Frontier in Concussion Research

Exploring ghrelin's neuroendocrine roles in gut-brain signaling, neuroinflammation, and emerging concussion science

Ghrelin is reshaping concussion science. Gain a neuroendocrine framework linking the gut-brain axis, neuroinflammation, and TBI recovery in 1 CE credit hour.

Functional Medicine
Ayla Wolf
Level:
4
-
Specialist
Credit Hours:
1
Price:

$

47.5

$

(

% off)

$

47.50
1 Choose your format.

Course Description

Concussion care has long relied on symptom management, but the underlying neuroendocrine environment shaping recovery remains underexplored in most clinical training. As evidence mounts around the gut-brain axis, ghrelin is emerging as a peptide with far broader significance than appetite regulation, with roles in neuroinflammation, neuroplasticity, and neuronal repair that have direct implications for post-concussion outcomes.

In this one-hour CE course, clinicians explore the mechanistic pathways through which ghrelin communicates across the gastrointestinal tract, vagus nerve, hypothalamus, and central nervous system. You will review preclinical findings on ghrelin-mediated inflammatory pathways, evaluate early clinical research on synthetic ghrelin therapy for TBI, and examine emerging evidence around post-traumatic headache and sensory dysfunction. This course equips you with a clinically sophisticated understanding of where the science is headed and what it means for your most complex concussion cases.

What you’ll learn:

  • Explain ghrelin's neuroendocrine roles beyond appetite in neuroinflammation and repair
  • Trace gut-brain axis signaling through the vagus nerve, hypothalamus, and CNS
  • Evaluate preclinical evidence on ghrelin-mediated inflammatory and neuroprotective pathways
  • Analyze early clinical research on synthetic ghrelin therapy in traumatic brain injury
  • Identify future research priorities including biomarkers and sex-specific hormonal factors

More About This Course

The science of concussion recovery is expanding well beyond rest protocols and symptom tracking. As functional neurology continues to integrate systems-level thinking, the gut-brain axis has emerged as one of the most compelling frontiers in neuroendocrine research. At the center of that conversation is ghrelin, a peptide long associated with hunger signaling that is now revealing a far more sophisticated biological profile. This course positions clinicians at the leading edge of that conversation, with a rigorous, evidence-grounded exploration of ghrelin's roles in neuroinflammation, neuroplasticity, neuronal repair, and traumatic brain injury recovery.

Beyond Hunger: Ghrelin, the Gut-Brain Axis, and a New Frontier in Concussion Research is a one-hour continuing education course that translates emerging preclinical and clinical research into a clinically meaningful framework. Participants move through the neuroanatomical pathways connecting the gastrointestinal tract, vagus nerve, hypothalamus, and central nervous system, examining how ghrelin participates in neuroendocrine signaling at each level. The course reviews preclinical studies on ghrelin-mediated inflammatory pathways, including the role of ferulic acid, and evaluates the early clinical evidence surrounding synthetic ghrelin therapy for concussion. Limitations of current research are addressed directly, and the course concludes by mapping future priorities including objective biomarkers, sex-specific hormonal influences, post-traumatic headache, and sensory dysfunction.

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This course is designed for licensed clinicians who regularly encounter post-concussion complexity and want a deeper mechanistic framework to contextualize what they are seeing clinically. It is particularly relevant for functional neurologists, acupuncturists, integrative practitioners, and any clinician working at the intersection of neuroendocrinology and brain health.

Components

Educational Syllabus

  • Ghrelin Reimagined: From Appetite Signal to Neuroendocrine Powerhouse
    • Clinicians gain a foundational reframe of ghrelin as a multifunctional neuroendocrine peptide, establishing the scientific basis for its roles in energy metabolism, neuroplasticity, and repair far beyond its original characterization.
  • The Gut-Brain Highway: Ghrelin, the Vagus Nerve, and CNS Communication
    • Explore the anatomical and physiological pathways connecting the gut, vagus nerve, hypothalamus, and brain. Clinicians build a systems-level map of how ghrelin participates in bidirectional gut-brain signaling relevant to neurological health.
  •  Inflammation, Neuroprotection, and the Preclinical Ghrelin Evidence Base
    • Review key preclinical findings on ghrelin-mediated inflammatory pathways, including ferulic acid interactions. Clinicians gain a working understanding of the neuroprotective mechanisms under investigation and their implications for TBI recovery.
  • Concussion's New Frontier: Clinical Research, Biomarkers, and What Comes Next
    • Evaluate early clinical trials on synthetic ghrelin therapy for concussion, examine the current evidence limitations, and identify the next horizon of research including sex-specific hormonal factors, objective biomarkers, and sensory dysfunction.

Venue, Hotels & Schedule

No items found.

Also includes

—
1
Months Medline Access
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Ability to resubscribe to keep access after
1
months
—
You have
1
month(s) access from the date you begin the course
—
Eligibility for Neurology Fellowship and Diplomate Examinations after the completion of 300+ hours of study
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Certificate of Completion
26SYNP | Beyond Hunger: Ghrelin, the Gut–Brain Axis, and a New Frontier in Concussion Research | On-Demand with Dr. Ayla Wolf26SYNP | Beyond Hunger: Ghrelin, the Gut–Brain Axis, and a New Frontier in Concussion Research | On-Demand with Dr. Ayla Wolf

Beyond Hunger: Ghrelin, the Gut–Brain Axis, and a New Frontier in Concussion Research

Ghrelin is reshaping concussion science. Gain a neuroendocrine framework linking the gut-brain axis, neuroinflammation, and TBI recovery in 1 CE credit hour.

Functional Medicine
Ayla Wolf
Level:
4
-
Specialist
Credit Hours:
1
Price:

$

47.5

$

(

% off)

$

47.50

The Carrick Institute team is ready to assist with enrollment, CE approval, or program planning. Email visit our CE Portal or Contact Us directly.

On Demand
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Live instruction · Anywhere
In Person
Hands-on · Full immersion
Ayla Wolf
|
DAOM, LAc, Dipl. OM (NCCAOM)
Assistant Professor of Physical Medicine
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