The science of neuroplasticity has reached a pivotal moment. For decades, clinicians working in neurorehabilitation have operated at the frontier of what was possible, applying experience and skill to some of the most complex recovery challenges in medicine. Now, foundational research in neural reorganization, cortical remapping, biomarker-guided prognosis, and plasticity-promoting adjuvant therapies is converging in ways that have direct implications for how rehabilitation is designed and delivered. This course, Exploiting Neural Plasticity to Enhance Neurorehabilitation, situates clinicians at that convergence and provides a rigorous, translational framework for understanding what the current science means at the point of care.

The course translates cutting-edge findings from animal models, large-scale human stroke trials, and emerging neuroimaging research into clear clinical insight. Clinicians will understand why repetition, intensity, salience, specificity, and task difficulty are not just general principles but neurobiologically grounded variables that directly influence cortical reorganization. They will also explore why individual patients with similar impairment profiles respond so differently to the same rehabilitation protocol, and what emerging biomarkers, including corticospinal tract integrity, motor evoked potentials, and genetic factors such as BDNF polymorphisms, may reveal about predicting and personalizing recovery.

This course is designed for licensed clinicians actively practicing in neurorehabilitation, functional neurology, physical therapy, occupational therapy, chiropractic neurology, or any discipline where neurological recovery is central to patient care. It is particularly well suited for clinicians managing post-stroke patients, traumatic brain injury cases, or complex neurological presentations where standard protocols have reached their limits and a more individualized, science-informed approach is needed.

Dr. Jeffrey Kleim is Associate Director of the School of Biological and Health Systems Engineering at Arizona State University and one of the most cited researchers in the translational neuroscience of rehabilitation. His laboratory work on cortical remapping after stroke, the behavioral determinants of plasticity, and the role of BDNF in motor recovery has directly informed rehabilitation science at an international level. His ability to translate complex neuroscience into clinically meaningful frameworks makes this course an exceptional resource for practitioners who want to lead at the intersection of science and patient care.