Courses

The 4 Neurochemical Priorities and Brain Basics

Decode the neurochemical environment driving your most complex cases

Learn to decode the neurochemical barriers blocking patient recovery using lab interpretation, nutrition, and brain physiology.

Functional Medicine
David Clark
Level:
2
-
Discoverer
Credit Hours:
25
Price:

$

1063

$

(

% off)

$

1063.00
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Course Description

Complex neurological cases often stall not from a failure of technique, but because metabolic and neurochemical barriers remain unaddressed. When the internal biochemical environment of the neuron is compromised, no amount of receptor-based rehabilitation can fully restore function. The gap between clinical skill and clinical outcomes frequently lives in the chemistry.

This course gives clinicians a rigorous, systems-level command of the neurochemical environment. You will learn to identify the four neurochemical priorities, interpret blood chemistry with functional precision, understand the physiology of excitotoxicity, neuroinflammation, and glial cell function, and translate that knowledge directly into patient care decisions. Dr. David Clark delivers graduate-level neuroscience in a clinically actionable framework built for licensed practitioners ready to work at the intersection of brain function and metabolic medicine.

What you’ll learn:

  • Apply the Four Neurochemical Priorities to identify metabolic barriers in any case
  • Interpret CBC and comprehensive metabolic panels using functional clinical ranges
  • Explain excitotoxicity mechanisms and identify promoters and modulators in practice
  • Analyze glial cell physiology and its role in neuroinflammation and BBB integrity
  • Connect neurotransmitter and receptor physiology to examination and symptom findings

More About This Course

The clinical gap most practitioners never see is not in their technique. It is in the neurochemical environment surrounding every neuron, synapse, and glial cell they are trying to rehabilitate. Clinical neurochemistry, blood chemistry interpretation, and functional nutrition form the invisible substrate beneath every patient outcome. Without fluency in these domains, even the most sophisticated receptor-based rehabilitation operates at a fraction of its potential.

This course delivers that fluency. Taught by Dr. David J. Clark, a clinician holding dual diplomates in clinical neurology and clinical nutrition alongside fellowships in functional neurology, brain injury rehabilitation, integrative medicine, and vestibular rehabilitation, Clinical Neurochemistry and Nutrition provides 25 hours of graduate-caliber instruction grounded in the current peer-reviewed literature. The curriculum spans the structural and physiological foundations of the neuron, the biochemistry of neurotransmission, the function and pathology of glial cells, blood-brain barrier regulation, excitotoxicity mechanisms, spreading depolarization, neuroinflammation, and the clinical application of comprehensive blood chemistry panels.

The course is organized around a practical decision-making framework, the Four Neurochemical Priorities, which gives clinicians a systematic method for identifying whether autoimmunity, cellular energy deficits, dysglycemia, or gastrointestinal and hepatic dysfunction are acting as barriers to patient recovery. This is not a protocol memorization course. Dr. Clark explicitly trains clinicians to understand physiology deeply enough to calculate clinical decisions rather than simply recall them.

Case studies anchor every concept to real patient presentations spanning epilepsy, stroke, migraine, chronic pain, ALS-mimicking gluten pathology, autoimmune encephalitis, and complex multisystem cases involving anemia, thyroid autoimmunity, and renal compromise. Blood chemistry panels including the comprehensive metabolic panel, CBC with differential, magnesium, phosphorus, GGT, LDH, and hemoglobin A1c are interpreted through both laboratory and functional lenses, with clear clinical decision trees for each finding.

This course is designed for licensed clinicians who are already skilled in neurological examination and rehabilitation and who are ready to address the metabolic and neurochemical dimension of their most challenging cases. Chiropractors, chiropractic neurologists, and functional medicine practitioners will find this training immediately applicable to practice. No prior biochemistry coursework is required, though a working knowledge of neuroanatomy will enhance the learning experience.

Components

Educational Syllabus

  • The Four Neurochemical Priorities That Drive Every Case
    • A systematic decision-making hierarchy covering autoimmunity, cellular energy, dysglycemia, and GI and liver function. Learn to identify which priority is blocking recovery before any other intervention.
  •  Brain Macrostructure and Evolutionary Function
    • Survey the evolutionary architecture of the brain and its functional logic. Understanding why the brain is built the way it is transforms how you interpret what happens when it breaks down.
  • Neurons, Synapses, and the Physics of Neural Communication
    • Master the structural and physiological foundations of neuronal function, from membrane potentials and action potentials to synaptic architecture and the tripartite synapse with astrocytes.
  • Neurotransmission and Receptor Pharmacology That Changes Everything
    • The identity of a neurotransmitter does not determine its effect. Receptor expression on the target cell does. This principle reframes how clinicians interpret neurotransmitter-based symptom patterns.
  • Glutamate, NMDA Receptors, and the Double Edge of Excitation
    • Glutamate drives plasticity and learning through LTP, but becomes lethal when uncontrolled. Clinicians gain a working model of excitotoxicity, NMDA receptor physiology, and magnesium's protective role.
  • Excitotoxicity in the Clinic - Promoters, Modulators, and Dietary Factors
    • Identify the clinical, nutritional, and biochemical factors that promote or inhibit excitotoxic cascades. Includes dietary glutamate load, homocysteine, zinc, magnesium, and reactive oxygen species.
  • Glial Cells as the Hidden Regulators of Brain Health
    • Astrocytes, oligodendrocytes, and microglia are not passive support cells. They regulate glutamate homeostasis, energy delivery, immune activation, and the integrity of every synapse in the brain.
  • Blood-Brain Barrier Integrity and Its Systemic Consequences
    • The BBB is not a wall. It is a dynamic regulatory interface. Understand what opens it, what it protects against, and how its disruption triggers neuroinflammatory cascades that can persist for years.
  • Neural Lipids, Membranes, and the Metabolic Cost of Myelin
    • DHA, arachidonic acid, cholesterol, and phospholipid dynamics define the physical and functional integrity of every neural membrane. Statins, statin alternatives, and clinical lipid applications are covered.
  • Brain Energy Metabolism and the Neuron-Glia Metabolic Partnership
    • Neurons outsource glycolysis to astrocytes and run on oxidative phosphorylation. Learn why this matters for understanding fatigue, cognitive impairment, and the metabolic vulnerability of neural tissue.
  • Neurochemistry of Epilepsy, Stroke, and Migraine
    • Spreading depolarization, autoimmune epilepsy, gluten-associated seizure disorders, and the stroke-migraine continuum are examined through a neurochemical lens with direct implications for case management.
  • Autoimmunity as a Neurochemical Priority
    • Autoimmune processes including Hashimoto's, anti-NMDA receptor encephalitis, GAD65 antibodies, and synapsin antibodies are examined as drivers of neurological dysfunction, not just systemic disease.
  • Clinical Cases That Connect Every System
    • Real patient cases spanning epilepsy, autoimmune encephalitis, anemia, renal compromise, and complex chronic presentations tie every course concept to clinical decisions made under real-world conditions.

Venue, Hotels & Schedule

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Also includes

—
3
Months Medline Access
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Ability to resubscribe to keep access after
3
months
—
You have
3
month(s) access from the date you begin the course
—
Eligibility for Neurology Fellowship and Diplomate Examinations after the completion of 300+ hours of study
—
Certificate of Completion
The 4 Neurochemical Priorities and Brain Basics | 992 | On-Demand by Dr. David ClarkThe 4 Neurochemical Priorities and Brain Basics | 992 | On-Demand by Dr. David Clark

The 4 Neurochemical Priorities and Brain Basics

Learn to decode the neurochemical barriers blocking patient recovery using lab interpretation, nutrition, and brain physiology.

Functional Medicine
David Clark
Level:
2
-
Discoverer
Credit Hours:
25
Price:

$

1063

$

(

% off)

$

1063.00

The Carrick Institute team is ready to assist with enrollment, CE approval, or program planning. Email visit our CE Portal or Contact Us directly.

On Demand
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In Person
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David Clark
|
DC, DACNB, FACFN, FABVR, FAAIM, FABBIR
Assistant Professor of Functional Neurology
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