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Regulation of Neurocognitive Dysfunction with Botanicals
How botanical protocols and biofilm science address the microbial roots of neuroinflammation and cognitive decline
Explore how gram-negative bacteria, biofilms, and LPS fuel cognitive decline and discover botanical clinical protocols that address root causes.
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Course Description
Chronic neuroinflammation is increasingly linked to microbial drivers that standard workups rarely capture. Lipopolysaccharides shed by gram-negative bacteria, biofilm-protected pathogens in the gut and oral cavity, and disrupted tight junctions in the blood-brain barrier are active contributors to the cognitive and neurodegenerative patterns clinicians encounter daily. Without addressing these upstream mechanisms, clinical interventions address symptoms while the underlying biology continues unchecked.
This course equips clinicians with a functional framework for identifying and targeting microbial sources of neuroinflammation. You will explore the role of LPS in microglial activation and Alzheimer's pathology, the science of biofilm formation and resistance, the systemic impact of oral dysbiosis, and evidence-informed botanical protocols shown to disrupt biofilm structure, support barrier integrity, and restore a healthier microbial environment. One credit hour of practical, translatable clinical science.
What you’ll learn:
- Explain how LPS from gram-negative bacteria triggers microglial activation and AD pathology
- Identify the three stages of biofilm formation and why they resist standard treatment
- Apply botanical compounds that disrupt biofilm structure and inhibit bacterial efflux pumps
- Recognize oral dysbiosis as a systemic driver of neuroinflammation and cognitive decline
- Design a functional botanical protocol targeting microbial sources of chronic brain inflammation
More About This Course
Neuroinflammation is no longer a peripheral concern in cognitive care. Emerging research in functional neuroscience and integrative medicine has established a clear and measurable relationship between gram-negative bacterial endotoxins, specifically lipopolysaccharides, and the microglial activation patterns that accelerate Alzheimer's disease pathology, cognitive impairment, and neurodegenerative progression. For clinicians working at the intersection of functional medicine and neurology, understanding this pathway is no longer optional. It is foundational.
This course, Regulation of Neurocognitive Dysfunction with Botanicals, offers clinicians a rigorous and clinically actionable framework for identifying the microbial contributors to chronic neuroinflammation and applying botanical interventions with demonstrated mechanisms of action. Participants will move beyond symptom-level analysis into the upstream biology of biofilm formation, LPS translocation across the gut and blood-brain barrier, oral-systemic dysbiosis connections, and the targeted use of condensed tannins, berberine, essential oils, and polyphenolic compounds that clinical and laboratory research has shown to disrupt biofilm architecture, inhibit efflux pump resistance, and support restoration of a balanced microbial environment. This is functional medicine applied with neurological precision.
This course is designed for licensed clinicians already working within integrative and functional frameworks who want to sharpen their clinical approach to complex, treatment-resistant cases involving cognitive decline, neurodegeneration, and chronic systemic inflammation. If you regularly encounter patients where standard interventions have reached a ceiling, this course offers a new layer of mechanistic understanding and practical protocol knowledge that translates directly into practice.
Instructor David Hartz brings extensive clinical experience in functional and integrative medicine with a particular focus on chronic disease, microbial dysfunction, and neurocognitive health. His approach is research-grounded, clinically tested, and deeply practical, reflecting years of working with patients for whom conventional approaches were insufficient.
Components
Educational Syllabus
- The Microbial Engine Driving Neurodegeneration
- Gram-negative bacteria shed LPS endotoxins that breach the blood-brain barrier, activate microglia, and accelerate Alzheimer's pathology. This topic establishes the mechanistic foundation connecting systemic microbial load to measurable cognitive decline.
- Biofilm Biology and Why Chronic Infection Persists
- Biofilms protect pathogens from antibiotics and immune clearance at resistance levels up to 5000 times normal thresholds. Learn the three-stage formation model and why resolving chronic infection requires targeting the biofilm first.
- Oral Dysbiosis as a Hidden Neuroinflammatory Source
- The oral microbiome seeds systemic and gut microbial environments continuously. Understand how periodontal biofilms contribute to LPS burden, neuropsychiatric risk, and Alzheimer's progression, and what targeted botanical oral care can change.
- Botanical Protocols That Disrupt Biofilms and Restore Balance
- Condensed tannins, berberine, essential oils, and polyphenolics demonstrate measurable biofilm disruption and efflux pump inhibition. Build a functional clinical protocol that reduces LPS burden, supports barrier integrity, and selectively restores beneficial microbiota.
Venue, Hotels & Schedule
Also includes
Regulation of Neurocognitive Dysfunction with Botanicals
Explore how gram-negative bacteria, biofilms, and LPS fuel cognitive decline and discover botanical clinical protocols that address root causes.
$
$
(
$
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